Vol 3, No 3 (2016)

Original articles

Polycystic ovary syndrome

Sosnova E.A.


In the clinical lecture the polycystic ovary syndrome (PCOS) is considered as the multiple endocrine disease associated with the disturbed function of ovaries, pancreas, adrenalcortex, the hypothalamus and the pituitarygland. The attention is drawn at the modern look at PCOS as a “diagnosis of exclusion”. There is presented information on basic theories of pathogenesis and differential diagnosis of PCOS from other hyperandrogenic conditions. The ultrasound semiotics of polycystic ovaries is reported in details. There are considered opportunities and perspectives of various modalities of therapies of PCOS.
V.F.Snegirev Archives of Obstetrics and Gynecology. 2016;3(3):116-129
pages 116-129 views

Modern aspects of pathogenesis and treatment of endometrial hyperplasia, uterine fibroids and adenomyosis

Kudrina E.A., Zholobova M.N., Masyakina A.V.


In the review there are presented modern aspects of pathogenesis of benign diseases of the uterus (uterine fibroids, adenomyosis, endometrial hyperplasia). There are highlighted questions of a differentiated approach to the treatment of given diseases.
V.F.Snegirev Archives of Obstetrics and Gynecology. 2016;3(3):130-135
pages 130-135 views

Pathophysiological role of free radical processes in pregnancies end in miscarriage

Sosnova E.A., Bolevich S.B., Pokaleneva M.S.


Pregnancy end in miscarriage proves to be the one of the main problems of modern obstetrics and gynecology. Miscarriage rate currently accounts for 15-27%. Among the causes of miscarriage there are discriminated genetic, anatomic, endocrine, infectious, immunologic, and thrombophilic factors. In the exclusion of all of above mentioned reasons the genesis of spontaneous abortion is considered to be unclear (idiopathic). In recent years, more and more often the attention of clinicians is attracted by pathophysiological aspects of the participation offree radical processes in molecular and cellular mechanisms of the development of alteration in pregnancy end in miscarriage. So far, information both on the generation of reactive oxygen species (ROS) by leukocytes and the state ofprotective antioxidant system in women with habitual loss ofpregnancy has failed to be systematized.
V.F.Snegirev Archives of Obstetrics and Gynecology. 2016;3(3):136-140
pages 136-140 views

Modern approaches to the management of patients with chronic endometritis

Unanyan A.L., Kossovich Y.M.


Chronic endometritis is the clinically relevant nosological form requiring the timely detection and treatment. Comprehensive stepped and pathogenetically grounded therapy for chronic endometritis in most of cases leads to the restoration of morphofunctional potential of the endometrium and as a consequence, it contributes to the successful implementation of the reproductive function.
V.F.Snegirev Archives of Obstetrics and Gynecology. 2016;3(3):141-148
pages 141-148 views

Obesity and metabolic disorders as a risk factor of endometrial hyperplasia, uterine fibroids and adenomyosis

Stanoevich I.V., Kudrina E.A., Zholobova M.N., Masyakina A.V., Kovaleva A.M.


The review deals with the role of endocrine and metabolic deteriorations in the development of overlapping clinically manifested benign hyperplastic lesion of endo- and myometrium. Hyperleptinemia is a powerful potentiating factor of endocrine diseases of the uterus. Modern correction of both endocrine and metabolic disorders is a key component of the comprehensive treatment and prevention of hyperplastic diseases of the uterus.
V.F.Snegirev Archives of Obstetrics and Gynecology. 2016;3(3):149-155
pages 149-155 views

Sample Biological Material Operating Procedure for the method of molecular-biological techniques (PCR diagnostics)

Kaptilnyy V.A.


Review describes a method of diagnostics with the use of the polymerase chain reaction (PCR diagnostics) of infections in patients in modern obstetric-gynecological practice. Particular attention is paid to urogenital tract pathogens to be diagnosed by the method of nucleic acid amplification. There are described the preparation for the study, purposes, the technology of amplification procedure. There is shown the difference in the detection of the DNA and RNA pathogen. The presented photographs show in detail all the stages of obtaining scrapings from the urogenital tract.
V.F.Snegirev Archives of Obstetrics and Gynecology. 2016;3(3):156-160
pages 156-160 views

Khirurgicheskaya pregravidarnaya podgotovka patsientok s operirovannoy sheykoy matki

Vrotskaya V.S., Popov A.A., Fedorov A.A.


Objective: to study and improve the productive outcomes in women with functional failure of the deformed cervix, cervical stump, utero-vaginal anastomosis through the introduction into clinical practice the cervical cerclage procedure.
V.F.Snegirev Archives of Obstetrics and Gynecology. 2016;3(3):161-162
pages 161-162 views

Vozmozhnosti 3D-angiografii v differentsial'noy diagnostike dobrokachestvennykh i zlokachestvennykh uzlov miometriya

Devitskiy A.A., Ozerskaya I.A.


Objective: To evaluate the possibility of 3D-angiography using vascularizational index (VI) in the tumors of the myometrium, with low and high proliferative activity.
V.F.Snegirev Archives of Obstetrics and Gynecology. 2016;3(3):162-162
pages 162-162 views

Sostoyanie fetoplatsentarnogo kompleksa pri bessimptomnoy infektsii nizhnikh otdelov mochevyvodyashchikh putey

Kaptil'nyy V.A., Krasil'shchikov I.M.


The study looks at asymptomatic bactriuria patients in the third trimestre of pregnancy who got either adequate or no antibiotic therapy, to establish its correlation with various pregnancy outcomes.
V.F.Snegirev Archives of Obstetrics and Gynecology. 2016;3(3):162-163
pages 162-163 views

Izmeneniya matochno-platsentarnogo krovotoka pri infektsionnom oslozhnenii beremennosti

Kaptil'nyy V.A., Krasil'shchikov I.M.


Many-year prospective clinical studies of the uteroplacental and fetal bloodflow were carried out with a special analysis of isolated disorders in the uterine arterial bloodflow by the results of dopplerometry after week 18 of gestation. The results indicated a relationship between disorders in the uteroplacental perfusion and foci of chronic infection of different location and demonstrated a prognostically unfavorable effect of these changes on pregnancy course and outcome.
V.F.Snegirev Archives of Obstetrics and Gynecology. 2016;3(3):163-164
pages 163-164 views

Otsenka sostoyatel'nosti rubtsa na matke posle operatsii kesareva secheniya. Varianty plastiki nesostoyatel'nogo rubtsa.

Kashchuk M.G., Ishchenko A.I., Tevlina E.V.


The research showed that the most effective method of plasty of a scar is a surgery laparotomic access doe to the low number of intra- and postoperative complications, reducing the probability of re-operation for reconstruction of the scar and perhaps further planning and management of pregnancy.
V.F.Snegirev Archives of Obstetrics and Gynecology. 2016;3(3):164-165
pages 164-165 views

Dienogest - sovremennye predstavleniya o gormonal'noy terapii v kompleksnom lechenii endometrioza

Klyukina L.A.


In the course of this work there has been done the evaluation of the influence of Dienogest in the key links of pathogenesis endometriosis and the possibility of its application as a hormonal therapy in a complex treatment of endometriosis, as well as in prevention of relapse of this disease.
V.F.Snegirev Archives of Obstetrics and Gynecology. 2016;3(3):165-166
pages 165-166 views

Akusherskie i perinatal'nye iskhody u pervorodyashchikh zhenshchin starshe 40 let

Kuleshova D.A., Gustovarova T.A., Ivanyan A.N., Kryukovskiy S.B., Babich E.N.


The aim of the study is to evaluate anamnesis, gestational complications, labor, delivery, puerperium and perinatal outcomes of the primiparous older than 40 years. It was a retrospective analysis of 80 case reports of the maternity Smolensk Clinical Hospital № 1. It was revealed that the parity of labor has no significant effect on the course of pregnancy and outcomes in postpartum women older than 40 years. The age factor alone and aggravated history are the main causes of gestation and childbirth complications in this group of women.
V.F.Snegirev Archives of Obstetrics and Gynecology. 2016;3(3):166-167
pages 166-167 views

Pyatiletniy opyt primeneniya ingibitora aromatazy v lechenii naruzhnogo genital'nogo endometrioza

Molotkov A.S., Yarmolinskaya M.I.


In the study we summarized our experience of treatment of endometriosis with prescribing of letrosole and orgametril. The effectiveness of aromatase inhibitor in curing pain and infertility in 130 cases of genital endometriosis were described.
V.F.Snegirev Archives of Obstetrics and Gynecology. 2016;3(3):167-168
pages 167-168 views

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