Vol 3, No 3 (2016)

In the clinical lecture the polycystic ovary syndrome (PCOS) is considered as the multiple endocrine disease associated with the disturbed function of ovaries, pancreas, adrenalcortex, the hypothalamus and the pituitarygland. The attention is drawn at the modern look at PCOS as a “diagnosis of exclusion”. There is presented information on basic theories of pathogenesis and differential diagnosis of PCOS from other hyperandrogenic conditions. The ultrasound semiotics of polycystic ovaries is reported in details. There are considered opportunities and perspectives of various modalities of therapies of PCOS.

Pregnancy end in miscarriage proves to be the one of the main problems of modern obstetrics and gynecology. Miscarriage rate currently accounts for 15-27%. Among the causes of miscarriage there are discriminated genetic, anatomic, endocrine, infectious, immunologic, and thrombophilic factors. In the exclusion of all of above mentioned reasons the genesis of spontaneous abortion is considered to be unclear (idiopathic). In recent years, more and more often the attention of clinicians is attracted by pathophysiological aspects of the participation offree radical processes in molecular and cellular mechanisms of the development of alteration in pregnancy end in miscarriage. So far, information both on the generation of reactive oxygen species (ROS) by leukocytes and the state ofprotective antioxidant system in women with habitual loss ofpregnancy has failed to be systematized.

The review deals with the role of endocrine and metabolic deteriorations in the development of overlapping clinically manifested benign hyperplastic lesion of endo- and myometrium. Hyperleptinemia is a powerful potentiating factor of endocrine diseases of the uterus. Modern correction of both endocrine and metabolic disorders is a key component of the comprehensive treatment and prevention of hyperplastic diseases of the uterus.

Objective: to study and improve the productive outcomes in women with functional failure of the deformed cervix, cervical stump, utero-vaginal anastomosis through the introduction into clinical practice the cervical cerclage procedure.

The study looks at asymptomatic bactriuria patients in the third trimestre of pregnancy who got either adequate or no antibiotic therapy, to establish its correlation with various pregnancy outcomes.

The research showed that the most effective method of plasty of a scar is a surgery laparotomic access doe to the low number of intra- and postoperative complications, reducing the probability of re-operation for reconstruction of the scar and perhaps further planning and management of pregnancy.

The aim of the study is to evaluate anamnesis, gestational complications, labor, delivery, puerperium and perinatal outcomes of the primiparous older than 40 years. It was a retrospective analysis of 80 case reports of the maternity Smolensk Clinical Hospital № 1. It was revealed that the parity of labor has no significant effect on the course of pregnancy and outcomes in postpartum women older than 40 years. The age factor alone and aggravated history are the main causes of gestation and childbirth complications in this group of women.