The influence of radical surgery on the uterus and appendages on the formation of metabolic syndrome

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Abstract


The aim of the study is to estimate the contribution of radical surgery on the uterus and appendages in the formation of the metabolic syndrome (MS). Material and methods. The study involved 100 patients, who underwent surgery on the pelvic organs in the extent of subtotal hysterectomy with bilateral adnexectomy or without it. Within 12 months after the operation in the dynamics there were investig TED changes in the body mass index (BMI), blood pressure (BP) and carbohydrate metabolism. Results. The removal of the uterus was established to fail to influence on the increase in body mass index, however, it has an impact on the indices of carbohydrate metabolism, in particular - on the change in the HOMA-IR index, and systolic blood pressure. The persistent increase in systolic blood pressure appeared to be the only index identified by the 12th month of the observation.

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About the authors

E. B Ginzburg

«Kaluga regional clinical hospital»

Kaluga, 248007, Russian Federation

Elena A. Sosnova

I.M. Sechenov First Moscow State Medical University; V.F. Snegirev Clinics of Obstetrics and Gynecology

Email: sosnova-elena@inbox.ru
Moscow, 119991, Russian Federation
MD, PhD, DSci., Professor of the Department of Obstetrics and Gynecology No 1, Medical Faculty of the I.M. Sechenov First Moscow State Medical University

References

  1. Reeves K.W., McLaughlin V., Fredman L., Ensrud K., Cauley J.Components of metabolic syndrome and risk of breast cancer by prognostic features in the study of osteoporotic fractures cohort. Cancer Causes Control. 2012; 23(8):1241-51.
  2. Thethi T., Kamiyama M., Kobori H. The link between the reninangiotensin-aldosterone system and renal injury in obesity and the metabolic syndrome. Curr. Hypertens. Rep. 2012;14(2):160.
  3. Nilas L., Loft A. Ovarian function after premenopausal hysterectomy. Ugeskr. Laeg. 1993; 155 (47): 3818-22.
  4. Кулаков В.И., Сметник В.П., Краснов В.Н., Мартынов В.И. и др. Хирургическая менопауза (пособие для врачей). М.; 2003.
  5. Rivera C.M., Grossardt B.R. et al. Increased cardiovavascular mortality after early bilateral oophorectomy. Menopause. 2009; 16: 15-23.
  6. Тювина Н.А., Балабанова В.В. Клиника и принципы терапии психических расстройств у женщин с послеоперационным климактерием. Журн. неврол. и психиатр. им. С.С. Корсакова. 1997; (2): 19.
  7. Подзолкова Н.М., Подзолков В.И., Никитина Т.Н., Шищенко В.В., Петричук С.В., Глазкова О.Л. и др. Особенности обменно-эндокринных нарушений у женщин после гистерэктомии с односторонней аднексэктомией на фоне метаболитной и антигипертензивной терапии. Российский вестник акушера-гинеколога. 2005; (1): 26.
  8. Hartmann B.W., Kirchengast S., Albrecht A. et al. Hysterectomy increases the symptomatology of postmenopausal syndrome. Gynec. Endocr. 1995; 9: 247-52.
  9. Lalinec-Michand M., Engelsmann F., Marino J. Depression after hysterectomy: a comparative study. Psychosomatics. 1988; 29: 307-14.
  10. Toth P., Lukacs H., Gimes G. et al. Clinical importance of vascular LH/hCG receptors - a review. Reprod. Biol. 2001; 1(2): 5-11.

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