妊娠期糖尿病实现正常血糖代偿的孕妇所产新生儿的主要人体测量指标
- 作者: Samchuk P.M.1,2, Azoeva E.L.1, Simacheva A.N.1
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隶属关系:
- Moscow State Clinical Hospital named after V.V. Veresaev
- I.M. Sechenov First Moscow State Medical University
- 期: 卷 12, 编号 2 (2025)
- 页面: 215-223
- 栏目: Original study articles
- ##submission.dateSubmitted##: 20.12.2024
- ##submission.dateAccepted##: 10.01.2025
- ##submission.datePublished##: 10.06.2025
- URL: https://archivog.com/2313-8726/article/view/643243
- DOI: https://doi.org/10.17816/aog643243
- EDN: https://elibrary.ru/PXKDHC
- ID: 643243
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论证。妊娠期糖尿病会增加母婴不良妊娠结局的发生风险。妊娠期糖尿病所致的高血糖可导致胎儿病态、巨大儿的发生,并增加患2型糖尿病、肥胖和高血压等疾病的风险。通过调整妊娠期糖尿病孕妇的生活方式可降低相关风险。
目的。评估妊娠期糖尿病孕妇在实现正常血糖代偿情况下所分娩新生儿的身高体重等生长指标。
材料与方法。对119例由经阴道自然分娩、头位足月单胎妊娠的孕妇所产新生儿进行了评估。于妊娠24–28周行口服葡萄糖耐量试验筛查妊娠期糖尿病。孕妇及其新生儿被分为两组:研究组(n=31)为经内分泌科医生依据静脉血浆葡萄糖参考值确诊的妊娠期糖尿病患者;对照组(n=88)为妊娠和分娩过程无并发症者。为评估两组新生儿主要人体测量指标的一致性,采用INTERGROWTH-21st百分位标准。研究结果的统计分析采用StatSoft软件(俄罗斯)进行。
结果。妊娠期糖尿病孕妇通过严格执行饮食治疗及适度运动,实现了正常血糖代偿。分娩时孕周为39–40周,与对照组无显著差异(p > 0.05)。新生儿的平均身长在三个身高亚组中进行了评估(47–50 cm、51–54 cm、≥55 cm)。在第1身高亚组中,妊娠期糖尿病组新生儿的平均身长为48.7 cm,无妊娠期糖尿病组为49.6 cm(p > 0.05);第2亚组中,两组平均身长均为52.1 cm(p > 0.05);第3亚组中分别为56.0 cm和55.2 cm(p > 0.05)。体重被划分为四个亚组进行评估(<3000 g、3050–3500 g、3550–3950 g、≥4000 g)。在第1体重亚组中,妊娠期糖尿病组新生儿的平均体重为2790 g,无妊娠期糖尿病组为2850 g (p > 0.05);在第2亚组中,分别为3330 g和3260 g(p > 0.05);第3亚组分别为3690 g和3770 g(p > 0.05);第4亚组分别为4110 g和4120 g(p > 0.05)。新生儿在妊娠期糖尿病组中的头围为35 [33; 36] cm,在无妊娠期糖尿病组中为34.7 [33; 37] cm (p > 0.05)。
结论。在无需使用胰岛素的情况下,妊娠期糖尿病孕妇通过遵循饮食治疗和适度体育活动,实现了正常血糖代偿。妊娠期糖尿病孕妇所产新生儿的主要人体测量指标与一般人群对照组无显著差异。足月分娩及缺乏需提前分娩处理的围产期并发症提示妊娠期糖尿病已获得良好控制。
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作者简介
Petr M. Samchuk
Moscow State Clinical Hospital named after V.V. Veresaev; I.M. Sechenov First Moscow State Medical University
编辑信件的主要联系方式.
Email: dr_samchuk@mail.ru
ORCID iD: 0000-0001-7882-8922
SPIN 代码: 7068-2310
MD, Dr. Sci. (Medicine), Professor
俄罗斯联邦, Moscow; MoscowEvelina L. Azoeva
Moscow State Clinical Hospital named after V.V. Veresaev
Email: ewelina.azoeva@yandex.ru
ORCID iD: 0000-0002-3711-2423
MD, Cand. Sci. (Medicine)
俄罗斯联邦, MoscowAngelina N. Simacheva
Moscow State Clinical Hospital named after V.V. Veresaev
Email: lina.sim02@list.ru
ORCID iD: 0009-0004-6276-0758
俄罗斯联邦, Moscow
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