Vol 2, No 2 (2015)

Original articles

Effectiveness of diagnostic methods of mother and fetus state

Atabieva D.A., Chilova R.A., Gadaeva I.V., Kovalev M.I., Pikuza T.V., Odnokopytnyy A.V., Zholobova M.N., Kaptilnyi V.A.


The etiology and pathogenesis of uterine inertia remain unclear, though this condition is responsible for 80% of cases with abnormal uterine activity. Timely correct evaluation of the uterine cervix readiness to labor (maturity) is essential for predicting the course of labor and particularly for determining the indications for and time of labor stimulation. Palpatory evaluation of the cervical status, ultrasonic cervicometry, dopplerometry, cardiotocography, fetal pulsometry are used to detect and correct some maternal and fetal abnormalities and thus improve the labor outcome.
V.F.Snegirev Archives of Obstetrics and Gynecology. 2015;2(2):4-10
pages 4-10 views

Iron metabolism in pre-eclampsia and eclampsia: hazards of erroneous views

Orlov Y.P., Lukach V.N., Govorova N.V., Baitugaeva G.A.


This review presents the modern view on iron metabolism in general and in pregnancy specifically. Opinions on the mechanism of anemia development in pregnancy are discussed, the protective role of anemia is emphasized, and the authors ’ opinion on the negative role of routine preventive oral iron is presented. Numerous well-based reasons indicate the negative impact of preventive iron and deny the efficiency of routine prescription of iron to pregnant patients. According to numerous data, prescription of iron in pregnancy promotes excessive stimulation of free radical oxidation, accumulation of lipid peroxides, and manifestation of eclampsia; moreover, it potentiates bacterial aggression and the development ofpyoseptic diseases, leading to pregnancy complications.
V.F.Snegirev Archives of Obstetrics and Gynecology. 2015;2(2):11-18
pages 11-18 views

Prognostic significance of isolated disorders in the uteroplacental perfusion in pregnancy

Kaptilnyi V.A.


Many-year prospective clinical studies of the uteroplacental and fetal bloodflow were carried out with a special analysis of isolated disorders in the uterine arterial bloodflow by the results of dopplerometry after week 20 of gestation. The results indicated a relationship between disorders in the uteroplacental perfusion and foci of chronic infection of different location and demonstrated a prognostically unfavorable effect of these changes on pregnancy course and outcome. Comparative analysis of corrective therapies in uteroplacental perfusion disorders included detection and elimination offoci of persistent infection (including asymptomatic infection) and drug therapy improving the vascular tone and blood rheology. Dipiridamole therapy proved to be highly effective in idiopathic disorders of uteroplacental perfusion.
V.F.Snegirev Archives of Obstetrics and Gynecology. 2015;2(2):19-25
pages 19-25 views

Perinatal aspects of papillomavirus infection

Baranovskaya E.I., Kustova M.A., Zhavaranak S.V.


The aim of this study was detection of the clinical and virological factors contributing to infection of the placenta and newborn’s airways by human papillomavirus (HPV). The HPV DNA was detected in 98 pregnant women, puerperae and their newborns, distributed into three hroups: 1) (n = 57) patients with abnormal cervix uteri or genital papillomatosis; 2) (n = 18) patients with HIV infection; and 3) control (n = 23). The HPV DNA was isolated from the genital tract in 84.2, 61.1, and 39.1% pregnant women in groups 1, 2, and 3, respectively, and was associated with abnormalities of the cervix uteri and genital papillomatosis. A total of 84% placentas were infected mainly by the same genotype of HPV, associated with vaginitis, cervix uteri disease and genital papillomatosis, cervical intraepithelial neoplasia, small for date fetus, and hydramnion. The number of HPV genotypes in the genital tract and the maternal viral charge determined the infection of the placenta and newborn’s airways.
V.F.Snegirev Archives of Obstetrics and Gynecology. 2015;2(2):26-30
pages 26-30 views

Urinary microflora in patients of reproductive age treated by oral glucocorticoids

Sosnova E.A., Tumbinskaya L.V.


Specimens of urinary cell precipitate from 27 women of reproductive age with total system diseases and renal diseases, treated by glucocorticoids, were studied by real time quantitative PCR (Femoflor kit, DNA-Technology, Russian Federation). Qualitative and quantitative composition of bacteria detected in the urine was evaluated.
V.F.Snegirev Archives of Obstetrics and Gynecology. 2015;2(2):30-35
pages 30-35 views

“Obstetrical” atypical hemolytic-uremic syndrome: difficult diagnosis?

Korotchaeva Y.V., Kozlovskaya N.L., Bondarenko T.V., Veselov G.A.


A case rare aGUS that developed late in the second trimester of pregnancy, and showed severe multiple organ pathology, including the kidneys, heart, lungs, nervous system and the placenta. As a result, early diagnosis and timely plazmotherapy started in conjunction with LMWH acute TMA eliminated with full restoration offunction of damaged organs.
V.F.Snegirev Archives of Obstetrics and Gynecology. 2015;2(2):36-41
pages 36-41 views

Summing up the experience gained in the treatment of puerperal mastitis in 642 patients in Russia. Comparative analysis with international recommendations

Pustotina O.A.


A total of 642 patients with puerperal mastitis were examined. The main disease agents and their sensitivity to antibacterial drugs were characterized. Modern methods for the treatment of puerperal mastitis and lactostasis preceding it were presented. Comparative analysis of the Russian and international recommendations was carried out.
V.F.Snegirev Archives of Obstetrics and Gynecology. 2015;2(2):42-47
pages 42-47 views

Urgent care in pre-eclampsia and its complications (eclampsia, HELLP syndrome). Federal clinical recommendations

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V.F.Snegirev Archives of Obstetrics and Gynecology. 2015;2(2):48-56
pages 48-56 views

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