Possibilities of antenatal pathology diagnostics in women after assisted reproductive technologies

Cover Page


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

PURPOSE: improving the efficiency of diagnosis of placental insufficiency using modern diagnostic methods.

MATERIALS AND METHODS: The analysis of individual cards, analysis of the gynecological history and somatic morbidity of 426 pregnant women who did not have somatic pathologies and underwent screenings in accordance with the current regulations were performed. The main group of them consisted of 290 women, who showed signs of chronic placental insufficiency at different stages of pregnancy. The control group consisted of 136 women who had no signs of placental insufficiency throughout their pregnancy.

RESULTS: It was revealed that the main reasons for the development of chronic placental insufficiency of the main group are preeclampsia (68.4%), the threat of termination of pregnancy (34.7%), burdened obstetric and gynecological history (32.5%), isoserological incompatibility (25.6%), pyelonephritis during pregnancy (14.2%) and anemia of pregnant women (13.2%). It was revealed that visualization of the fetoplacental complex and measurement of peripheral resistance in the umbilical artery during the second trimester of pregnancy are not very informative. To reduce the negative impact of fetoplacental insufficiency and its timely diagnosis, it is necessary to use radiation methods for examining the mother–placenta–fetus system.

CONCLUSIONS: For timely diagnosis of fetoplacental insufficiency and reduction of its negative impact, it is necessary to use radiation methods of studying the mother-placenta-fetus system.

Full Text

Restricted Access

About the authors

Tat’yana A. Kamaeva

Khakass State University named after N.F. Katanov

Author for correspondence.
Email: tatyankamaev@yandex.ru

Cand. Sci. (Med.), Associate Professor

Russian Federation, 90 Lenin Str., Abakan, 655001, Republic of Khakassia

References

  1. Kulakov VI, Serov VN, Barashnev YuI, et al. A guide to safe motherhood. Moscow: Triada-Kh; 1998. P. 34–86. (In Russ).
  2. Kolpinskiy G, Kamaeva T. Predictive value of ultrasound study in the diagnosis of early-stage pregnancy after IVF. Modern Science: actual problems of theory and practice. 2017;(3–4):94–97. (In Russ).
  3. Hansmann M. Routine ultrasound in Germany 10–20–30 weeks schedule. Ultrasound Obstet Gynecol. 1995;6:7–8.
  4. Kuznetsov MI. Evaluation of fetal respiratory movements during echographic examination using B-/M-scan mode. Ul’trazvukovaya diagnostika v akusherstve, ginekologii i pediatrii. 2018;(1):48–50. (In Russ).
  5. Hampl V, Jakoubek V. Regulation of fetoplacental vascular bed by hypoxia. Physiol Res. 2009;58, Suppl.2:S87–S93. doi: 10.33549/physiolres.931922
  6. Hunt K, Kennedy SH, Vatish M. Definitions and reporting of placental insufficiency in biomedical journals: a review of the literature. Eur J Obstet Gynecol Reprod Biol. 2016;205:146–149. doi: 10.1016/j.ejogrb.2016.08.029
  7. Gagnon R. Placental insufficiency and its consequences. Eur J Obstet Gynecol Reprod Biol. 2003;110, Suppl.1:S99–S107. doi: 10.1016/s0301-2115(03)00179-9
  8. Wardinger JE, Ambati S. Placental Insufficiency. StatPearls. 2020. [Internet]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK563171/
  9. Miller SL, Huppi PS, Mallard C. The consequences of fetal growth restriction on brain structure and neurodevelopmental outcome. J Physiol. 2016;594(4):807–823. doi: 10.1113/JP271402
  10. Lo JO, Roberts VHJ, Schabel MC, et al. Novel Detection of Placental Insufficiency by Magnetic Resonance Imaging in the Nonhuman Primate. Reprod Sci. 2018;25(1):64–73. doi: 10.1177/1933719117699704
  11. Spencer R, Rossi C, Lees M, et al.; EVERREST Consortium. Achieving orphan designation for placental insufficiency: annual incidence estimations in Europe. BJOG. 2019;126(9):1157–1167. doi: 10.1111/1471-0528.15590
  12. Luo J, Abaci Turk E, Bibbo C, et al. In vivo quantification of placental insufficiency by BOLD MRI: a human study. Sci Rep. 2017;7(1):3713. doi: 10.1038/s41598-017-03450-0
  13. Murthi P, Kalionis B, Rajaraman G, Keogh RJ, Da Silva Costa F. The role of homeobox genes in the development of placental insufficiency. Fetal Diagn Ther. 2012;32(4):225–230. doi: 10.1159/000339657

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2021 Eco-Vector



СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ:
ПИ № ФС 77 - 86335 от 11.12.2023 г.  
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ:
ЭЛ № ФС 77 - 80633 от 15.03.2021 г.



This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies