Treatment of habitual pregnancy miscarriage of various origins
- Authors: Unanyan A.L.1, Pivazyan L.G.1, Zakaryan A.A.1, Siordiya A.A.1, Ishchenko A.I.1
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Affiliations:
- I.M. Sechenov First Moscow State Medical University
- Issue: Vol 9, No 1 (2022)
- Pages: 13-21
- Section: Reviews
- URL: https://archivog.com/2313-8726/article/view/100908
- DOI: https://doi.org/10.17816/2313-8726-2022-9-1-13-21
Cite item
Abstract
Habitual pregnancy miscarriage is one of the serious problems of reproductive health in the modern world. Habitual miscarriage is defined as the spontaneous termination of two or more pregnancies before the fetus reaches viability from conception to 24 weeks of pregnancy. However, some differences of opinion are determined among specialists in habitual miscarriage. Some experts in their clinical practice for habitual miscarriages use the definition of three or more consecutive miscarriages. Habitual miscarriage occurrence varies from 0.5 to 2.3%, but the exact prevalence is very difficult to estimate, which depends on the used definition. The pathogenesis of habitual miscarriage is determined based on the age of the mother and the gestational age of the fetus. Habitual miscarriage can be caused by chromosomal errors, autoimmune disorders, endometrial dysfunction, endocrinopathies, hormonal and metabolic disorders, infections, and uterine anatomical defects. Currently available treatments target suspected risk factors for miscarriage, although the effectiveness of many medical interventions appears to be controversial.
This study aimed to evaluate the effectiveness of treatments for habitual miscarriage of various origins, such as antiphospholipid syndrome, subclinical hypothyroidism, and idiopathic habitual miscarriage.
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About the authors
Ara L. Unanyan
I.M. Sechenov First Moscow State Medical University
Author for correspondence.
Email: 9603526@mail.ru
ORCID iD: 0000-0002-2283-2356
MD, Dr. Sci. (Med.), professor
Russian Federation, 119991, MoscowLaura G. Pivazyan
I.M. Sechenov First Moscow State Medical University
Email: laurapivazyan98@gmail.com
ORCID iD: 0000-0002-6844-3321
V-year student
Russian Federation, 119991, MoscowAraksya A. Zakaryan
I.M. Sechenov First Moscow State Medical University
Email: araksya.zakaryan99@mail.ru
ORCID iD: 0000-0003-0919-465X
IV-year student
Russian Federation, 119991, MoscowArchil A. Siordiya
I.M. Sechenov First Moscow State Medical University
Email: 9603526@mail.ru
MD, Cand. Sci. (Med.), assistant professor
Russian Federation, 119991, MoscowAnatoliy I. Ishchenko
I.M. Sechenov First Moscow State Medical University
Email: 9603526@mail.ru
MD, Dr. Sci. (Med.), Professor, Head of the Department of Obstetrics and Gynecology
Russian Federation, 119991, MoscowReferences
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