Yuri Anatolyevich Ovchinnikov and I. The Big is Seen from a Distance

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I have talked about Yuri Anatolyevich in many popular articles. We have more than 30 publications in common. In particular, more than 10 are on RNA polymerase:, 5 are on ATPase, 1 (out of 3) is devoted to photoaffinity modification of the active centers of RNA polymerase; 18 articles and patents on interferons, 10 of which involve Yuri Anatolyevich: 6 of the most significant, 7 articles and patents (3 of which involve Yuri Anatolyevich) are devoted to the problem of a vaccine against the Hepatitis A virus.

I was part of the team that received the USSR State Prize in 1981 for work on RNA polymerase, headed by Yuri Anatolyevich. It should also be noted that with the active assistance of Yu. A. Ovchinnikov, industrial production of interferon was organized, which I called Reaferon (recombinant alpha interferon), and I, together with other participants in this difficult work, was awarded the Lenin Prize. Reaferon is sold in pharmacies to this day and will be used for a very long time. I have provided this data so that it is clear how close our cooperation was.

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作者简介

E. Sverdlov

National Research Center “Kurchatov Institute”

编辑信件的主要联系方式.
Email: edsverd@gmail.com
俄罗斯联邦, pl. Acad. Kurchatova 1, Moscow, 123182

参考

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  2. Lipkin V.M., Sverdlov E.D., Ovchinnikov Yu.A. // Proc. Indian Natn. Sci. Acad. 1982. P. 56–68.
  3. Marchenko T.V., Lipkin V.M., Chertov Yu.O., Sverdlov E.D., Ovchinnikov Yu.A. // Int. J. Quantum Chem. 1981. V. 20. P. 283–289. https://doi.org/10.1002/qua.560200202
  4. Ovchinnikov Yu.A., Monastyrskaia G.S., Gubanov V.V., Guriev S.O., Chertov O.Yu., Modianov N.N., Grinkevich V.A., Makarova I.A., Marchenko T.V., Polovnikova I.N. // Dokl. Akad. Nauk SSSR. 1980. V. 253. P. 994–998.
  5. Ovchinnikov Iu.A., Monastyrskaia G.S., Gubanov V.V., Guriev S.O., Salomatina I.S., Shuvaeva T.M., Lipkin V.M., Sverdlov E.D., Shemakina M.M. // Dokl. Ros. Akad. Nauk. 1981. V. 261. P. 763–768.
  6. Ovchinnikov Y.A., Monastyrskaya G.S., Gubanov V.V., Gureyev S.O., Chertov O.Y., Modyanov N.N., Grinkevich V.A., Makarova I.A., Mrchenko T.V., Polovnikova I.N. // Europ. J. Biochem. 1981. V. 116. P. 621– 629.
  7. Ovchinnikov Yu.A., Monastyrskaya G.S., Gubanov V.V., Salomatina I.S., Shuvaeva T.M., Lipkin V.M., Sverdlov E.D. // Rus. J. Bioorg. Chem. 1981. V. 7. P. 1107–1112.
  8. Ovchinnikov Y.A., Monastyrskaya G.S., Guriev S.O., Kalinina N.F., Sverdlov E.D., Gragerov A.I., Bass I.A., Kiver I.F., Moiseyeva E.P., Igumnov V.N., Mindlin S.Z., Nikiforov V.G., Khesin R.B. // Mol. Gen. Genet. 1983. V. 190. P. 344–348. https://doi.org/10.1007/bf00330662
  9. Овчинников Ю.А., Свердлов Е.Д., Липкин В.М., Монастырская Г.С., Чертов О.Ю., Губанов В.В., Гурьв С.О., Модянов Н.Н., Гринкевич В.А., Макарова И.А., Марченко Т.В., Половникова И.Н. // Биоорг. химия. 1980. Т 6. С. 655–665.
  10. Sverdlov, E.D,. Tsarev, S.A. Levitan, T.L. Lipkin, V.M. Modyanov, N.N. Grachev, M.A. Saychikov, E.F. Pletnev, A.G., Ovchinnikov, Yu.A. / Interaction of E. coli RNA Polymerase with Substrates During Initiation of RNA Synthesis at Different Promoters in Macromolecules in the Functioning Cell / Salvatore F., Marino G., Volpe P., Eds., Springer, Boston M.A., 1979, Plenum Press, New York. https://doi.org/10.1007/978-1-4684-3465-1_10
  11. Broude N.E., Sverdlov E.D., Ovchinnikov Yu.A. The Family of Human Na+,K+-ATPase Genes, Organization and Function of the Eucaryotic Genome / Abstracts Seventh German-Soviet Symposium, 1987, April 2–4, Springer, Heidelberg.
  12. Ovchinnikov Yu.A., Monastyrskaia G.S., Broude N.E., Ushkarev Yu.A., Dolganov G.M. // Dokl. Akad. Nauk SSSR. 1986. V. 287. P. 1251–1254.
  13. Ovchinnikov Yu.A., Modyanov N.N., Broude N.E., Petrukhin K.E., Grishin A.V., Arzamazova N.M., Aldanova N.A., Monastyrskaya G.S., Sverdlov E.D. // FEBS Lett. 1986. V. 201. P. 237–245. https://doi.org/10.1016/0014-5793(86)80616-0
  14. Ovchinnikov Yu.A., Monastyrskaya G.S., Broude N.E., Allikmets R.L., Ushkaryov Yu.A., Melkov A.M., Smirnov Yu.V., Malyshev I.V., Dulubova I.E., Petrukhin K.E. // FEBS Lett. 1987. V. 213. P. 73–80. https://doi.org/10.1016/0014-5793(87)81467-9
  15. Ovchinnikov Yu.A., Monastyrskaya G.S., Broude N.E., Ushkaryov Yu.A., Melkov A.M., Smirnov Yu.V., Malyshev I.V., Allikmets R.L., Kostina M.B., Dulubova I.E. // FEBS Lett. 1988. V. 233. P. 87–94.
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  17. Sverdlov E.D., Tsarev S.A., Kuznetsova N.F. // FEBS Lett. 1980. V. 112. P. 296–298. https://doi.org/10.1016/0014-5793(80)80202-X
  18. Ovchinnikov Yu.A., Sverdlov E.D., Monastyrskaia G.S., Tsarev S.A., Zaitseva E.M. // Mol. Biol. 1984. V. 18. P. 48–59.
  19. Ovchinnikov Yu.A., Sverdlov E.D., Tsarev S.A., Khodkova E.M., Monastyrskaia G.S. // Dokl. Akad. Nauk SSSR. 1982. V. 262. P. 725–728.
  20. Ovchinnikov Iu.A., Sverdlov E.D., Tsarev S.A., Monastyrskaia G.S., Khodkova E.M. // Dokl. Akad. Nauk SSSR. 1983. V. 268. P. 996–1000. PMID: 6187523
  21. Ovchinnikov Yu.A., Sverdlov E.D., Tsarev S.A. // Electronic J.Inform. Technol. Construct. 1982. V. 1–6. P. 265.
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  23. Ovchinnikov, Yu.A., Zhdanov V.M., Khodkova E.M., Efimov V.A., Chakhmakhcheva D.G., Kustetsov V.P. // Labor-Med. (GIT-Verlag Giebeler). 1983. V. 6. P. 385– 392.
  24. Sverdlov E.D., Monastyrskaya G.S., Budowsky E.I., Grachev M.A. // FEBS Lett. 1972. V. 28. P. 231–235. https://doi.org/10.1016/0014-5793(72)80719-1
  25. Sverdlov E.D., Monastyrskaya G.S., Chestukhin A.V., Budowsky E.I. // FEBS Lett. 1973. V. 33. P. 15–17. https://doi.org/10.1016/0014-5793(73)80148-6
  26. Ovchinnikov Iu.A., Dolganov G.M., Efimov V.A., Monastyrskaia G.S., Sverdlov E.D. // Dokl. Akad. Nauk SSSR. 1979. V. 248. P. 1486–1491.
  27. Balayan M.S., Kusov Yu.Yu., Andjaparidze A.G., Tsarev S.A., Sverdlov E.D., Chizhikov V.E., Blinov V.M., Vasilenko S.K. // FEBS Lett. 1989. V. 247. P. 425–428. https://doi.org/10.1016/0014-5793(89)81384-5
  28. Kusov I.I., Kazachkov I.A., Grabko V.I., Nastashenko T.A., Balaian M.S., Tsarev S.A., Rokhlina T.O., Sverdlov E.D. // Dokl. Akad. Nauk SSSR. 1987. V. 294. P. 731–734
  29. Sverdlov E.D., Tsarev S.A., Markova S.V., Rostapshov V.M., Azhikina T.L., Chenov I.P., Gorbalenya A.E., Kolesnikova M.S., Romanova L.I., Teterina N.L. // FEBS Lett. 1989. V. 257. P. 354–356. https://doi.org/10.1016/0014-5793(89)81570-4
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  31. Шемякин, М. М., Арбузов, Ю. А., Колосов, М. Н., Овчинников, Ю. А. // Докл. АН СССР. 1985. T. 133. C. 1121–1124.

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2. Fig. 1. RNA polymerase substrates. I. γ-anilide adenosine triphosphate, II. γ-azidoanilide adenosine triphosphate, III. γ-azidoanilide guanosine triphosphate. Circles denote the α-P³² group.

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