Yuri Anatolyevich Ovchinnikov and I. The Big is Seen from a Distance

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Abstract

I have talked about Yuri Anatolyevich in many popular articles. We have more than 30 publications in common. In particular, more than 10 are on RNA polymerase:, 5 are on ATPase, 1 (out of 3) is devoted to photoaffinity modification of the active centers of RNA polymerase; 18 articles and patents on interferons, 10 of which involve Yuri Anatolyevich: 6 of the most significant, 7 articles and patents (3 of which involve Yuri Anatolyevich) are devoted to the problem of a vaccine against the Hepatitis A virus.

I was part of the team that received the USSR State Prize in 1981 for work on RNA polymerase, headed by Yuri Anatolyevich. It should also be noted that with the active assistance of Yu. A. Ovchinnikov, industrial production of interferon was organized, which I called Reaferon (recombinant alpha interferon), and I, together with other participants in this difficult work, was awarded the Lenin Prize. Reaferon is sold in pharmacies to this day and will be used for a very long time. I have provided this data so that it is clear how close our cooperation was.

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E. D. Sverdlov

National Research Center “Kurchatov Institute”

Author for correspondence.
Email: edsverd@gmail.com
Russian Federation, pl. Acad. Kurchatova 1, Moscow, 123182

References

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2. Fig. 1. RNA polymerase substrates. I. γ-anilide adenosine triphosphate, II. γ-azidoanilide adenosine triphosphate, III. γ-azidoanilide guanosine triphosphate. Circles denote the α-P³² group.

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