DETECTION OF METRONIDAZOLE AND FAMPRIDINE BY NMR AT ZERO AND ULTRALOW MAGNETIC FIELD

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Abstract

In this work the biocompatible molecules — metronidazole and fampridine — were successfully hyperpolarized using parahydrogen via the signal amplification by reversible exchange approach. The nuclear magnetic resonance (NMR) signals from both molecules were detected at zero- to ultralow magnetic field (ZULF) using commercially available rubidium vapor magnetometer from QuSpin.

About the authors

D. B Burueva

International Tomography Center Siberian Branch of Russian Academy of Sciences

Author for correspondence.
Email: burueva@tomo.nsc.ru
Novosibirsk, Russia

J. Eills

Helmholtz-Institut Mainz; GSI Helmholtzzentrum für Schwerionenforschung GmbH; Institute of Physics, Johannes Gutenberg-Universität

Email: burueva@tomo.nsc.ru
Mainz, Germany; Darmstadt, Germany; Mainz, Germany

R. Picazo-Frutos

Helmholtz-Institut Mainz; GSI Helmholtzzentrum für Schwerionenforschung GmbH; Institute of Physics, Johannes Gutenberg-Universität

Email: burueva@tomo.nsc.ru
Mainz, Germany; Darmstadt, Germany; Mainz, Germany

K. V Kovtunov

International Tomography Center Siberian Branch of Russian Academy of Sciences

Email: burueva@tomo.nsc.ru
Novosibirsk, Russia

D. Budker

Helmholtz-Institut Mainz; GSI Helmholtzzentrum für Schwerionenforschung GmbH; Institute of Physics, Johannes Gutenberg-Universität; Department of Physics, University of California

Email: burueva@tomo.nsc.ru
Mainz, Germany; Darmstadt, Germany; Mainz, Germany; Berkeley, USA

I. V Koptyug

International Tomography Center Siberian Branch of Russian Academy of Sciences

Email: koptyug@tomo.nsc.ru
Novosibirsk, Russia

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