Strategies for treating pregnant women with hepatitis B and C
- Authors: Kaptilnyy V.A.1, Reyshtat D.Y.1, Berishvili M.V.1, Zholobova M.N.1
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Affiliations:
- I.M. Sechenov First Moscow State Medical University
- Issue: Vol 8, No 4 (2021)
- Pages: 177-184
- Section: Reviews
- URL: https://archivog.com/2313-8726/article/view/89955
- DOI: https://doi.org/10.17816/2313-8726-2021-8-4-177-184
- ID: 89955
Cite item
Abstract
This multilateral review provides current knowledge regarding pregnancy and infection with hepatitis B virus (HBV) and hepatitis C virus (HCV), as well as discusses modern methods to reduce mother-to-child transmission (MTCT) of these infections. Maternal HBV or HCV infection is associated with adverse outcomes of pregnancy and childbirth, including MTCT. In countries, including the United States, where postpartum HBV vaccination and immunoprophylaxis with hepatitis B immunoglobulin have been introduced, MTCT has generally decreased to approximately 5%. Unlike that for HBV infection, there is no available or recommended therapy to reduce the risk of MTCT of HBV infection, and the risk remains at 3–10%. MTCT of HCV can be minimized if do not use obstetric care and avoid birth injuries. Young women with HCV should be referred for treatment after childbirth, and newborns should be closely monitored to rule out infection. New, more affordable, and better tolerated HCV treatment regimens are now emerging that will help reduce the number of infected women and infants.
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About the authors
Vitaliy A. Kaptilnyy
I.M. Sechenov First Moscow State Medical University
Author for correspondence.
Email: 1mgmu@mail.ru
ORCID iD: 0000-0002-2656-132X
MD, Cand. Sci. (Med.), assistant professor
Russian Federation, 119991, MoscowDiana Yu. Reyshtat
I.M. Sechenov First Moscow State Medical University
Email: Diana.reyshtat@mail.ru
ORCID iD: 0000-0002-5789-3415
V-year student
Russian Federation, 119991, MoscowManana V. Berishvili
I.M. Sechenov First Moscow State Medical University
Email: berishvilim@gmail.com
ORCID iD: 0000-0002-0834-0806
MD, Cand. Sci. (Med.), assistant professor
Russian Federation, 119991, MoscowMariya N. Zholobova
I.M. Sechenov First Moscow State Medical University
Email: angel1345@mail.ru
ORCID iD: 0000-0003-2842-2910
MD, Cand. Sci. (Med.), assistant professor
Russian Federation, 119991, MoscowReferences
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