DIAGNOSIS AND PHARMACOTHERAPY OF PELVIC INFLAMMATORY DISEASES IN WOMEN



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Abstract

The article is devoted to modern issues of etiology, in particular, the theory of biofilms as the most promising direction of research. Biofilms are most often represented by the association of microorganisms in which they, through coexistence in close contacts, acquire new properties, expressed in an atypical clinical picture. This determines problems of rapid diagnosis and pathogenesis, in which both the local and systemic secondary immunodeficiency state is put in the forefront, autoimmune inflammation and reactions of free radical oxidation. The most typical symptoms and signs of inflammatory diseases of the pelvic organs include, in particular, chronic salpingo-oophoritis - a common nosological item from this group, which has important social and demographic significance, since the most affected group, according to statistics, are women of reproductive age. The emphasis was placed on approaches to diagnosis using not only data from the collected history and physical examination but also methods based on modern instrumental and minimally invasive methods. Special attention was paid to measures aimed at correcting risk factors and preventing this disease, etiotropic therapy with the presentation of a specific scheme of the most rational antibiotic therapy, pathogenetic and symptomatic treatment to alleviate the condition before the eradication of the pathogenic microorganism or their association in the composition of biofilms and cure patients, and correction such unpleasant complications as vaginal dysbiosis, which can develop against a background of powerful antibiotic therapy and is not a measure of inadequate treatment and change of the selected regimen.

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About the authors

Vsevolod V. Skvortsov

Volgograd State Medical University

Email: vskvortsov1@ya.ru
MD, Ph.D., DSci., Associate Professor of the Department of Propaedeutics of Internal Diseases of the Volgograd State Medical University, Volgograd, 400131, Russian Federation Volgograd, 400131, Russian Federation

M. V Lunkov

Volgograd State Medical University

Volgograd, 400131, Russian Federation

E. M Skvortsova

Medical Clinic Medsi

Volgograd, 400131, Russian Federation

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