妊娠期卵巢肿块发生的预测可能性

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详细

背景。妊娠期卵巢肿块是一种常见病理状况，其发生率可达3.2%。然而，现有文献中关于卵巢肿块切除术后复发的研究较少，而这些数据可能有助于预测其再次发生的可能性。

目的。评估基于评分量表数据建立预测规则的可行性，以预测妊娠期卵巢肿块的发生。

材料与方法。本研究纳入100名妊娠中晚期的女性，并分为两组：第1组（研究组，n=50）妊娠期发生卵巢肿块，包括初次发生（首次妊娠前）及复发（再次妊娠前）；第2组（对照组，n=50）无卵巢肿块病史的妊娠女性（既往妊娠及当前妊娠均未出现病变）。

结果。研究建立了两个预测模型，并在随机选取的24例妊娠期首次或复发性卵巢肿块患者中进行了测试。预测结果与实际情况的符合率较高，首次发生病例的预测准确度为83%，复发性病例的预测准确度为62%。

结论。预测模型的应用可用于诊断评估妊娠期卵巢肿块的首次及复发性发生风险。这种方法提高了卵巢病变的诊断和预防准确性，同时有助于在超声检查或手术干预之前选择合适的治疗和管理策略。

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作者简介

Dinara A. Fatkullina

Bashkir State Medical University

编辑信件的主要联系方式.
Email: mukhamadzhanova91@gmail.com
ORCID iD: 0000-0002-9615-2134
SPIN 代码: 4661-4751

Graduate Student

俄罗斯联邦, 3 Lenin st, Ufa, 450008

Alfiya G. Yashchuk

Bashkir State Medical University

Email: alfiya_galimovna@mail.ru
ORCID iD: 0000-0003-2645-1662
SPIN 代码: 2607-9150

MD, Dr. Sci. (Medicine), Professor

俄罗斯联邦, 3 Lenin st, Ufa, 450008

Ilnur Ir. Musin

Bashkir State Medical University

Email: ilnur-musin@yandex.ru
ORCID iD: 0000-0001-5520-5845
SPIN 代码: 4829-1179

MD, Dr. Sci. (Medicine), Assistant Professor

俄罗斯联邦, 3 Lenin st, Ufa, 450008

Eugeny M. Gareev

Bashkir State Medical University

Email: gem46@list.ru
ORCID iD: 0000-0002-6561-0892
SPIN 代码: 9325-1326

Cand. Sci. (Biology), Assistant Professor

俄罗斯联邦, 3 Lenin st, Ufa, 450008

参考

  1. Adilgereyeva AS, Zhurabekova GA. Epidemiology of benign neoplasms of the ovaries and prospects of their early diagnostics. Astana Medical Journal. 2020;(3):33–40. EDN: CQITPQ
  2. Mallika B, Chakravarthy VK, Rao DR. Histopathological study of ovarian tumours. J Evolution Med Dent Sci. 2019;8 (9):551–554. doi: 10.14260/jemds/2019/122
  3. Zahra F. Pattern of benign ovarian cysts in Qatari women. Qatar Medical Journal. 2017;2016(2):17. doi: 10.5339/qmj.2016.17
  4. Graham L. ACOG releases guidelines on management of adnexal masses. Am Fam Physician. 2008;77(9):1320–1323.
  5. Pearl JP, Price RR, Tonkin AE, et al. SAGES guidelines for the use of laparoscopy during pregnancy. Surg Endosc. 2017;31(10):3767–3782. doi: 10.1007/s00464-017-5637-3
  6. Davydova IYu, Karseladze AI, Kuznetsov VV, Meshcheriakova LA. Surgical treatment of recurrent borderline serous ovarian tumor. Problems in Oncology. 2021;67(4):538–546. doi: 10.37469/0507-3758-2021-67-4-538-546 EDN: KXNLHF
  7. Gubler EV. Computational methods of analysis and recognition of pathological processes. Leningrad: Medicine; 1978. 294 p. (In Russ.) EDN: ZIQHWB
  8. Kochubeykov BK. Biostatistics. Kazan: KSMU; 2014. 135 p. (In Russ.)
  9. Boev VM, Borshchuk EL, Ekimov AK, Begun DN. Guidelines for ensuring the solution of biomedical problems using the Statistica 10 program. Orenburg: Yuzhny Ural; 2014. 208 p. (In Russ.) EDN: TVFQZX
  10. Grjibovski AM. Analysis of nominal data (independent observations). Ekologiya cheloveka (Human Ecology). 2008;(6):58–68. EDN: KXIIFZ
  11. Pavlovich TP, Cherevko AN, Labzo SS, et al. Assessment of risks and chances during medical research. Minsk: BSMU; 2021. 20 р. (In Russ.)
  12. Boyko AV. Modern aspects of echografical diagnostics of neoplasms of ovaries during pregnancy. Family Medicine. 2019;(5-6):39–42. doi: 10.30841/2307-5112.5-6.2019.193378 EDN: MYGLEF
  13. Serebrennikova KG, Kuznetsova EP, Halilov RZ. The risk factors by musses and benign ovarian tumors. Ural Medical Journal. 2010;(6):111–115. EDN: MWJYRP
  14. Babichev VN, Marova EI, Kuznetsova TA, et al. Hormonal signal receptor mechanisms in neuroendocrinology. Problems of Endocrinology. 2000;46(5):33–35. doi: 10.14341/probl11874 EDN: ISSFUU
  15. Seidell JS. The wordwide epidemic of obesity. In: Guy-Grand B, Aihaud G, editors. Progress in obesity research. 8th International congress on obesity. London: John Libbey and Company Ltd.; 2019. Р. 47–53.
  16. Raikova AA. Obesity as a risk factor for menstrual cycle disorders in women of reproductive age. V.F. Snegirev Archives of Obstetrics and Gynecology. 2016;3(4):213–214. doi: 10.17816/aog35388 EDN: XGVDND
  17. Nesterenko EI, Solomatin DM. Artificial termination of pregnancy as a risk factor for gynecological morbidity in women. Public Health and Disease Prevention. 2005;(1):38–43. (In Russ.)
  18. Rusanova NE. Reproductive aspects of demographic policy. In: Russia: trends and development prospects. Moscow: Institut nauchnoi informatsii po obshchestvennym naukam RAN; 2023. Р. 483–485. (In Russ.) EDN: AWPNPV
  19. Davidov AI, Tchaban OV. Endometriomas (endometrioid cysts) of ovaries: malignization risk, its causes and prophylactic measures. Gynecologic Oncology. 2012;(2):39–48. EDN: SZRFOP
  20. Sidorova IS, Unanyan AL. Particular features of ovarian cysts and endometriosis treatment. Obstetrics, Gynecology and Reproduction. 2011;5(1):29–32. EDN: NYCBLD
  21. Timmerman D, Planchamp F, Bourne T, et al. ESGO/ISUOG/IOTA/ESGE Consensus Statement on preoperative diagnosis of ovarian tumors. Ultrasound Obstet Gynecol. 2021;58(1):148–168. doi: 10.1002/uog.23635
  22. Babic A, Cramer DW, Kelemen LE, et al. Predictors of pretreatment CA125 at ovarian cancer diagnosis: a pooled analysis in the Ovarian Cancer Association Consortium. Cancer Causes Control. 2017;28(5):459–468. doi: 10.1007/s10552-016-0841-3
  23. Johnson CC, Kessel B, Riley TL, et al. The epidemiology of CA-125 in women without evidence of ovarian cancer in the prostate, lung, colorectal and ovarian cancer (PLCO) screening trial. Gynecol Oncol. 2008;110(3):383–389. doi: 10.1016/j.ygyno.2008.05.006
  24. Bobrov MYu, Balashov IS, Filippova ES, et al. Assessment of microRNA expression in retrocervical endometriotic lesions. Akusherstvo i Ginekologiya. 2018;(6):55–61. doi: 10.18565/aig.2018.6.55-61 EDN: XRYMDR
  25. Cancer Genome Atlas Research Network. Integrated genomic analyses of ovarian carcinoma. Nature. 2011;474(7353):609–615. doi: 10.1038/nature10166
  26. Berek JS, Kehoe ST, Kumar L, Friedlander M. Cancer of the ovary, fallopian tube, and peritoneum. Int J Gynaecol Obstet. 2018;143 Suppl 2:59–78. doi: 10.1002/ijgo.12614
  27. Pavlova NG, Arzhanova ON, Zainulina MS, Kolobov AV. Placental insufficiency: an educational and methodological guide. St. Petersburg: N-L; 2007. 32 р. (In Russ.) EDN: QLRJGF
  28. Kulakov VI, Ordzhonikidze MF, Tyutyunnik VL. Placental insufficiency and infection: a guide for doctors. Moscow; 2004. 496 р. (In Russ.)
  29. Manannikova TN. Diagnosis and treatment of benign ovarian tumors during pregnancy [dissertation abstract]. Moscow; 2001. 24 р. (In Russ.)
  30. Manannikova TN. Tactics of management of pregnant women with benign ovarian tumors. Bulletin of the Russian Association of Obstetricians and Gynecologists. 2001;(1):65–67. (In Russ.)
  31. Pestrikova TYu, Yurasova EA, Yurasov IV. Tactics of management of pregnant women with tumors and tumor-like formations of the reprodctive system. In: Problems of reproduction. 2007. Р. 123. (In Russ.)
  32. Brown R, Gagnon R, Delisle MF. Cervical insufficiency and cervical cerclage. J Obstet Gynaecol Can. 2013;35(12):1115–1127. doi: 10.1016/S1701-2163(15)30764-7
  33. Levakov SA, Borovkova EI, Sheshukova NA, Borovkov IM. Management of patients with cervical insufficiency. Obstetrics, Gynecology and Reproduction. 2016;10(2):64–69. doi: 10.17749/2313-7347.2016.10.2.064-069 EDN: WIRTZN
  34. Sundtoft I, Langhoff-Roos J, Sandager P, et al. Cervical collagen is reduced in non-pregnant women with a history of cervical insufficiency and a short cervix. Acta Obstet Gynecol Scand. 2017;96(8):984–990. doi: 10.1111/aogs.13143
  35. Thakur M, Jenkins SM, Mahajan K. Cervical insufficiency. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2024.
  36. Lee SE, Romero R, Park CW, et al. The frequency and significance of intraamniotic inflammation in patients with cervical insufficiency. Am J Obstet Gynecol. 2008;198(6):633.e1–633.e6338. doi: 10.1016/j.ajog.2007.11.047
  37. Bogolepova NYu, Andreeva MV, Andreev VA. Trigger factors of the development of inflammatory diseases of the uterus. Mother and Baby in Kuzbass. 2014;(2):79–81. EDN: SXVTWL
  38. Wei M, Jin X, Li TC, et al. A comparison of pregnancy outcome of modified transvaginal cervicoisthmic cerclage performed prior to and during pregnancy. Arch Gynecol Obstet. 2018;297(3):645–652. doi: 10.1007/s00404-017-4636-x
  39. Koch LI, Nazarenko LP, Cukanova ZhV, Satysheva IV. Connective tissue dysplasia is one possible reason of cervical incompetence. Journal of Obstetrics and Womans Diseases. 2009;58(4):45–49. (In Russ.) EDN: ITTCRV
  40. Belenky AG. Hypermobility of joints, nomenclature, clinical manifestations and treatment. Consilium Medicum. 2001;3(9):421–425. (In Russ.) EDN: WZKQWT
  41. Kadurina TI, Abakumova LN. Estimation of the severity of the nondifferentiated connective tissue dysplasia in children. Medical News of North Caucasus. 2008;10(2):15–21. EDN: MWNUON
  42. Klemenov AV. Undifferentiated dysplasia of the connective tissue of the heart. Moscow; 2005. 136 р. (In Russ.)
  43. Mitelev DA, Shklyar SP. Neuroorthopedic and vertebroneurological aspects of dysplasia of the connective tissue in teenagers. Kazan Medical Journal. 2007;88(5):138–139. EDN: ULFMIN
  44. Shilyaev PP, Shalnova N. Connective tissue dysplasia and its connection with the pathology of internal organs in children and adults. Current Pediatrics. 2003;2(5):61–67. (In Russ.)
  45. Vinetskaya MI, Iomdina EN, Makhmudova FR, Boltayeva ZK, et al. Changes in the content of certain trace elements in the hair of children and adolescents with progressive myopia. Russian Annals of Ophthalmology. 1988;(5):35–36. (In Russ.)
  46. Fujii K, Tanzer ML. Aldehyde content and cross-linking of type III collagen. Biochem Biophys Res Commun. 1976;69(1):128–134. doi: 10.1016/s0006-291x(76)80282-3

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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
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