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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">V.F.Snegirev Archives of Obstetrics and Gynecology</journal-id><journal-title-group><journal-title xml:lang="en">V.F.Snegirev Archives of Obstetrics and Gynecology</journal-title><trans-title-group xml:lang="ru"><trans-title>Архив акушерства и гинекологии им. В.Ф. Снегирева</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2313-8726</issn><issn publication-format="electronic">2687-1386</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">676889</article-id><article-id pub-id-type="doi">10.17816/aog676889</article-id><article-id pub-id-type="edn">QZDALD</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original study articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные исследования</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="zh"><subject>Original study articles</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Comparative study of sexual function in women with radiation-induced vaginal stenosis before and after treatment</article-title><trans-title-group xml:lang="ru"><trans-title>Сравнительное исследование сексуальной функции женщин с радиационно-индуцированным стенозом влагалища до и после лечения</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>放射性诱导阴道狭窄女性治疗前后性功能的比较研究</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0855-7754</contrib-id><contrib-id contrib-id-type="spin">8566-4281</contrib-id><name-alternatives><name xml:lang="en"><surname>Gubanova</surname><given-names>Elena G.</given-names></name><name xml:lang="ru"><surname>Губанова</surname><given-names>Елена Геннадьевна</given-names></name><name xml:lang="zh"><surname>Gubanova</surname><given-names>Elena G.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>ekaz4ntseva@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2645-1662</contrib-id><contrib-id contrib-id-type="spin">2607-9150</contrib-id><name-alternatives><name xml:lang="en"><surname>Yashchuk</surname><given-names>Alfiya G.</given-names></name><name xml:lang="ru"><surname>Ящук</surname><given-names>Альфия Галимовна</given-names></name><name xml:lang="zh"><surname>Yashchuk</surname><given-names>Alfiya G.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Medicine), Professor</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор</p></bio><bio xml:lang="zh"><p>MD, Dr. Sci. (Medicine), Professor</p></bio><email>alfiya_galimovna@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5520-5845</contrib-id><contrib-id contrib-id-type="spin">4829-1179</contrib-id><name-alternatives><name xml:lang="en"><surname>Musin</surname><given-names>Ilnur I.</given-names></name><name xml:lang="ru"><surname>Мусин</surname><given-names>Ильнур Ирекович</given-names></name><name xml:lang="zh"><surname>Musin</surname><given-names>Ilnur I.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Medicine), Professor of the Department</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор кафедры</p></bio><bio xml:lang="zh"><p>MD, Dr. Sci. (Medicine), Professor of the Department</p></bio><email>ilnur-musin@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1641-9952</contrib-id><name-alternatives><name xml:lang="en"><surname>Battalova</surname><given-names>Gyuzel Yu.</given-names></name><name xml:lang="ru"><surname>Батталова</surname><given-names>Гюзель Юрьевна</given-names></name><name xml:lang="zh"><surname>Battalova</surname><given-names>Gyuzel Yu.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Medicine), Professor of the Department</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор кафедры</p></bio><bio xml:lang="zh"><p>MD, Dr. Sci. (Medicine), Professor of the Department</p></bio><email>guzel.batt@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Bashkir State Medical University</institution></aff><aff><institution xml:lang="ru">Башкирский государственный медицинский университет</institution></aff><aff><institution xml:lang="zh">Bashkir State Medical University</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2025-08-17" publication-format="electronic"><day>17</day><month>08</month><year>2025</year></pub-date><pub-date date-type="pub" iso-8601-date="2025-10-26" publication-format="electronic"><day>26</day><month>10</month><year>2025</year></pub-date><volume>12</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><issue-title xml:lang="zh"/><fpage>317</fpage><lpage>325</lpage><history><date date-type="received" iso-8601-date="2025-03-06"><day>06</day><month>03</month><year>2025</year></date><date date-type="accepted" iso-8601-date="2025-05-11"><day>11</day><month>05</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, Эко-Вектор</copyright-statement><copyright-statement xml:lang="zh">Copyright ©; 2025,</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2027-10-26"/></permissions><self-uri xlink:href="https://archivog.com/2313-8726/article/view/676889">https://archivog.com/2313-8726/article/view/676889</self-uri><abstract xml:lang="en"><p><bold>Background:</bold> One of the common complications following radical surgery and chemoradiotherapy of the pelvic organs is radiation-induced vaginal stenosis, which exerts a persistent negative impact on female sexual function and requires addressing the issue of providing assistance to women in this regard.</p> <p><bold>Aim:</bold> The work aimed to evaluate sexual satisfaction in patients with radiation-induced vaginal stenosis using the Female Sexual Function Index before and after individually tailored treatment.</p> <p><bold>Methods:</bold> The study included 25 women: 10 patients with radiation-induced vaginal stenosis treated with hyaluronic acid injections combined with dilator therapy (group 1); 5 patients who required surgical intervention—vaginal reconstruction with a Martius–Symmonds myocutaneous flap (group 2); and 10 women in the control group (group 3).</p> <p><bold>Results:</bold> The main Female Sexual Function Index domains were assessed: desire, arousal, lubrication, orgasm, satisfaction, and pain. Before treatment, the total scores in group 1 and group 2 were lower compared with the control group, with the severity of sexual dysfunction corresponding to low scores. After treatment, all domains of sexual quality of life improved in group 1, with the highest scores recorded in arousal (5.13 ± 0.29) and satisfaction (4.52 ± 0.41) domains, followed by orgasm (5.00 ± 0.43), desire (4.80 ± 0.45), lubrication (4.80 ± 0.32), and pain (4.20 ± 0.39). After treatment, the satisfaction score in group 2 was the highest, 3.92 ± 0.65, and the orgasm score was 3.84 ± 0.44. The other domains showed the following values: lubrication, 3.48 ± 0.68; desire, 3.48 ± 0.97; arousal, 3.48 ± 1.01; pain, 3.04 ± 1.30.</p> <p><bold>Conclusion:</bold> The findings may serve as an incentive for further research into the treatment of radiation-induced vaginal stenosis and, consequently, improving the sexual quality of life in women.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Обоснование.</bold> Одним из часто встречающихся осложнений после радикального хирургического вмешательства и химиолучевой терапии на органах малого таза является радиационно-индуцированный стеноз влагалища, который оказывает стойкое негативное влияние на женскую сексуальную функцию и требует решения вопроса о помощи женщинам в данном вопросе.</p> <p><bold>Цель.</bold> Оценить сексуальную удовлетворённость пациенток с радиационно-индуцированным стенозом влагалища с помощью опросника «Индекс женской сексуальной функции» изначально и после индивидуально подобранного метода лечения.</p> <p><bold>Методы.</bold> В исследовании учувствовали 25 женщин, из них 10 — с радиационно-индуцированным стенозом влагалища, лечение которых основывалось на использовании гиалуроновой кислоты с одновременной дилатирующей терапией (1-я группа), пяти пациенткам понадобилось хирургическое вмешательство — реконструкция влагалища с использованием кожно-мышечно-жирового лоскута Martius–Symmonds (2-я группа), 10 женщин составили контрольную группу (3-я группа).</p> <p><bold>Результаты.</bold> Оценивали основные составляющие опросника «Индекс женской сексуальной функции»: влечение, возбуждение, любрикация, оргазм, удовлетворение и боль. До лечения в 1-й и 2-й группах суммарный балл был ниже в сравнении с контрольной группой, при этом выраженность степени сексуальной дисфункции соответствовала низким показателям. После лечения все показатели качества сексуальной жизни в 1-й группе пациенток увеличились и распределились следующим образом: в доменах «возбуждение» (5,13±0,29) и «удовлетворение половой жизнью» (4,52±0,41) женщины выставляли наиболее высокие значения, далее — оргазм (5,00±0,43), влечение (4,80±0,45), любрикация (4,80±0,32) и боль (4,20±0,39). Критерий удовлетворённости половой жизнью после лечения во 2-й группе имел наиболее высокий результат — 3,92±0,65, показатель достижения оргазма составил 3,84±0,44. Другие домены имели следующие значения: любрикация — 3,48±0,68, влечение — 3,48±0,97, возбуждение — 3,48±1,01, боль — 3,04±1,30.</p> <p><bold>Заключение.</bold> Полученные результаты исследования могут служить стимулом для дальнейших поисков лечения радиационно-индуцированного стеноза влагалища и, как следствие, улучшения качества сексуальной жизни женщин.</p></trans-abstract><trans-abstract xml:lang="zh"><p>论证：放射性诱导阴道狭窄是根治性盆腔手术及放化疗后常见的并发症之一，对女性性功能造成持续性负面影响，因此亟需解决为患者提供帮助的问题。</p> <p>目的：采用“女性性功能指数”（Female Sexual Function Index）问卷，评估放射性诱导阴道狭窄患者在个体化治疗前后的性满意度。</p> <p>材料与方法：本研究共纳入25名女性，其中10例为放射性诱导阴道狭窄患者，接受透明质酸联合扩张疗法（第1组）；5例患者需要手术治疗，行Martius–Symmonds皮肤–肌肉–脂肪瓣阴道重建术（第2组）；另有10例女性构成对照组（第3组）。</p> <p>结果：评估了“女性性功能指数”的六个领域：性欲、性唤起、润滑、性高潮、性生活满意度及性交疼痛。治疗前，第1组和第2组的总评分低于对照组，同时性功能障碍的严重程度对应于较低水平的指标。治疗后，第1组所有指标均有提高，其中“性唤起”（5.13±0.29）和“性生活满意度”（4.52±0.41）得分最高，其次依次为性高潮（5.00±0.43）、性欲（4.80±0.45）、润滑（4.80±0.32）及性交疼痛（4.20±0.39）。第2组治疗后，性生活满意度指标最高3.92±0.65，性高潮得分为3.84±0.44。其他领域的得分依次为：润滑3.48±0.68、性欲3.48±0.97、性唤起3.48±1.01和性交疼痛3.04±1.30。</p> <p>结论：研究结果可作为进一步探索放射性诱导阴道狭窄治疗方法的推动力，并进而改善女性性生活质量。</p></trans-abstract><kwd-group xml:lang="en"><kwd>radiation-induced vaginal stenosis</kwd><kwd>Martius–Symmonds flap</kwd><kwd>sexual satisfaction</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>радиационно-индуцированный стеноз влагалища</kwd><kwd>лоскут Martius–Symmonds</kwd><kwd>сексуальная удовлетворённость</kwd></kwd-group><kwd-group xml:lang="zh"><kwd>放射性诱导阴道狭窄</kwd><kwd>Martius–Symmonds皮瓣</kwd><kwd>性满意度</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Kachnic LA, Bruner DW, Qureshi MM, Russo GA. 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