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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">V.F.Snegirev Archives of Obstetrics and Gynecology</journal-id><journal-title-group><journal-title xml:lang="en">V.F.Snegirev Archives of Obstetrics and Gynecology</journal-title><trans-title-group xml:lang="ru"><trans-title>Архив акушерства и гинекологии им. В.Ф. Снегирева</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2313-8726</issn><issn publication-format="electronic">2687-1386</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">630676</article-id><article-id pub-id-type="doi">10.17816/aog630676</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Reviews</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Научные обзоры</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Pregnancy and labor in patients with uterine fibroids</article-title><trans-title-group xml:lang="ru"><trans-title>Течение беременности и родов у пациенток с миомой матки</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>子宫肌瘤患者的妊娠及分娩过程</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7830-2290</contrib-id><contrib-id contrib-id-type="spin">2925-9948</contrib-id><name-alternatives><name xml:lang="en"><surname>Dobrokhotova</surname><given-names>Yulia E.</given-names></name><name xml:lang="ru"><surname>Доброхотова</surname><given-names>Юлия Эдуардовна</given-names></name><name xml:lang="zh"><surname>Dobrokhotova</surname><given-names>Yulia E.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Medicine), Professor</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор</p></bio><bio xml:lang="zh"><p>MD, Dr. Sci. (Medicine), Professor</p></bio><email>pr.dobrohotova@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-2767-8995</contrib-id><contrib-id contrib-id-type="spin">7707-5981</contrib-id><name-alternatives><name xml:lang="en"><surname>Khachatryan</surname><given-names>Aznar S.</given-names></name><name xml:lang="ru"><surname>Хачатрян</surname><given-names>Азнар Сааковна</given-names></name><name xml:lang="zh"><surname>Khachatryan</surname><given-names>Aznar S.</given-names></name></name-alternatives><address><country country="AM">Armenia</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Medicine), Assistant Professor</p></bio><bio xml:lang="ru"><p>канд. мед. наук, доцент</p></bio><bio xml:lang="zh"><p>MD, Cand. Sci. (Medicine), Assistant Professor</p></bio><email>aznardoc@yahoo.com</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8155-8775</contrib-id><contrib-id contrib-id-type="spin">5753-4380</contrib-id><name-alternatives><name xml:lang="en"><surname>Ilyina</surname><given-names>Irina Yu.</given-names></name><name xml:lang="ru"><surname>Ильина</surname><given-names>Ирина Юрьевна</given-names></name><name xml:lang="zh"><surname>Yu.</surname><given-names>Irina Yu.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Medicine), Professor of the Department</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор кафедры</p></bio><bio xml:lang="zh"><p>MD, Dr. Sci. (Medicine), Professor of the Department</p></bio><email>iliyina@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8738-868X</contrib-id><contrib-id contrib-id-type="spin">7962-4941</contrib-id><name-alternatives><name xml:lang="en"><surname>Ibragimova</surname><given-names>Djamilia M.</given-names></name><name xml:lang="ru"><surname>Ибрагимова</surname><given-names>Джамиля Магомедовна</given-names></name><name xml:lang="zh"><surname>Ibragimova</surname><given-names>Djamilia M.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Medicine), Assistant Professor</p></bio><bio xml:lang="ru"><p>канд. мед. наук, доцент</p></bio><bio xml:lang="zh"><p>MD, Cand. Sci. (Medicine), Assistant Professor</p></bio><email>dgam81@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0677-2952</contrib-id><contrib-id contrib-id-type="spin">2723-5711</contrib-id><name-alternatives><name xml:lang="en"><surname>Narimanova</surname><given-names>Metanat R.</given-names></name><name xml:lang="ru"><surname>Нариманова</surname><given-names>Метанат Рафиговна</given-names></name><name xml:lang="zh"><surname>Narimanova</surname><given-names>Metanat R.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Medicine), Assistant Professor</p></bio><bio xml:lang="ru"><p>канд. мед. наук, доцент</p></bio><bio xml:lang="zh"><p>MD, Cand. Sci. (Medicine), Assistant Professor</p></bio><email>safarovametanat@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0009-6999-4553</contrib-id><name-alternatives><name xml:lang="en"><surname>Platova</surname><given-names>Elena S.</given-names></name><name xml:lang="ru"><surname>Платова</surname><given-names>Елена Сергеевна</given-names></name><name xml:lang="zh"><surname>Platova</surname><given-names>Elena S.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Medicine), Assistant Professor</p></bio><bio xml:lang="ru"><p>канд. мед. наук, доцент</p></bio><bio xml:lang="zh"><p>MD, Cand. Sci. (Medicine), Assistant Professor</p></bio><email>lena.platova2015@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7117-7642</contrib-id><contrib-id contrib-id-type="spin">5387-8115</contrib-id><name-alternatives><name xml:lang="en"><surname>Kauseva</surname><given-names>Olga I.</given-names></name><name xml:lang="ru"><surname>Каусева</surname><given-names>Ольга Игоревна</given-names></name><name xml:lang="zh"><surname>Kauseva</surname><given-names>Olga I.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Ultrasound Diagnostics Doctor</p></bio><bio xml:lang="ru"><p>врач ультразвуковой диагностики</p></bio><bio xml:lang="zh"><p>Ultrasound Diagnostics Doctor</p></bio><email>olga.kauseva@gmail.com</email><xref ref-type="aff" rid="aff3"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Pirogov Russian National Research Medical University</institution></aff><aff><institution xml:lang="ru">Российский национальный исследовательский медицинский университет им. Н.И. Пирогова</institution></aff><aff><institution xml:lang="zh">Pirogov Russian National Research Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Yerevan State Medical University</institution></aff><aff><institution xml:lang="ru">Ереванский государственный медицинский университет</institution></aff><aff><institution xml:lang="zh">Yerevan State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">City Clinical Hospital No. 1 named after N.I. Pirogov</institution></aff><aff><institution xml:lang="ru">Городская клиническая больница № 1 им. Н.И. Пирогова</institution></aff><aff><institution xml:lang="zh">City Clinical Hospital No. 1 named after N.I. Pirogov</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2025-02-24" publication-format="electronic"><day>24</day><month>02</month><year>2025</year></pub-date><pub-date date-type="pub" iso-8601-date="2025-02-24" publication-format="electronic"><day>24</day><month>02</month><year>2025</year></pub-date><volume>12</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><issue-title xml:lang="zh"/><fpage>5</fpage><lpage>14</lpage><history><date date-type="received" iso-8601-date="2024-04-23"><day>23</day><month>04</month><year>2024</year></date><date date-type="accepted" iso-8601-date="2025-01-10"><day>10</day><month>01</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, Эко-Вектор</copyright-statement><copyright-statement xml:lang="zh">Copyright ©; 2025,</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2027-04-11"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-nd/4.0/</ali:license_ref></license></permissions><self-uri xlink:href="https://archivog.com/2313-8726/article/view/630676">https://archivog.com/2313-8726/article/view/630676</self-uri><abstract xml:lang="en"><p>This review examines the etiology, pathogenesis, clinical manifestations, and impact of uterine fibroids on reproductive function. Particular attention is given to infertility, pregnancy, and labor in patients with fibroids. Uterine fibroids may be asymptomatic or present with various symptoms, including menstrual irregularities and pelvic pain. The review discusses the effect of fibroids on conception, fetal development, and the risk of pregnancy and labor complications. The influence of fibroids on pregnancy outcomes is determined by their location, size, and number. With the increasing maternal age of women planning pregnancy, the prevalence of uterine fibroids in this population is also rising. As a result, organ-preserving surgical approaches aimed at optimizing reproductive outcomes and reducing pregnancy complications have become a primary treatment strategy. However, the best management strategy that minimizes complications and alleviates symptoms remains undefined. Treatment decisions should be individualized, taking into account multiple factors and requiring thorough patient evaluation. The review underscores the importance of early detection and prevention of pregnancy-related complications in patients with uterine fibroids. Further research is essential to refine preventive measures and optimize treatment strategies for this condition.</p></abstract><trans-abstract xml:lang="ru"><p>В представленном обзоре обсуждаются вопросы этиологии, патогенеза, клинических проявлений и влияния миомы матки на репродуктивную функцию женщины. Особое внимание уделяется проблемам бесплодия, беременности и родов при наличии миомы. Отмечается, что данное заболевание может протекать бессимптомно или сопровождаться различными жалобами, такими как нарушения менструального цикла, болевой синдром и другие. Также обсуждается влияние миомы матки на возможность забеременеть, на развитие плода, на частоту осложнений беременности и родов. Влияние миомы матки на наступление и течение беременности определяется локализацией, размерами и количеством узлов. В настоящее время возраст женщин, планирующих беременность, постепенно растёт, в связи с чем увеличивается вероятность наличия у них миомы матки. Поэтому основным хирургическим направлением являются органосохраняющие операции с целью подготовки пациенток к беременности и уменьшения рисков развития осложнений. Какое именно лечение может привести к оптимальному результату, наименьшему количеству осложнений, уменьшению симптомов, на сегодняшний день окончательно не установлено, это зависит от многих факторов и требует тщательного отбора и обследования пациенток. В заключение обзора подчёркивается важность раннего выявления и предотвращения осложнений беременности при миоме матки, отмечается, что дальнейшие исследования в этой области могут помочь в разработке эффективных методов профилактики и лечения данного заболевания.</p></trans-abstract><trans-abstract xml:lang="zh"><p>本综述探讨了子宫肌瘤的病因、发病机制、临床表现及其对女性生殖功能的影响，重点关注该疾病对不孕、妊娠及分娩的影响。研究表明，子宫肌瘤可能为无症状，也可能伴随月经紊乱、疼痛综合征等各种临床表现。此外，本文还讨论了子宫肌瘤对受孕能力、胎儿发育以及妊娠和分娩并发症发生率的影响。子宫肌瘤对妊娠的发生及进展的影响取决于其位置、大小及数量。近年来，计划妊娠的女性年龄逐渐上升，因此，子宫肌瘤的患病率也相应增加。因此，当前的手术策略主要以保留子宫的方式进行，以帮助患者备孕并降低妊娠并发症的风险。然而，目前尚未明确哪种治疗方案最优，可最大程度减少并发症并改善症状。治疗选择受多种因素影响，需要对患者进行详细筛查和个体化评估。本综述最后强调了早期发现子宫肌瘤及预防妊娠并发症的重要性，并指出该领域的进一步研究可能有助于开发更有效的预防和治疗策略。</p></trans-abstract><kwd-group xml:lang="en"><kwd>uterine fibroids</kwd><kwd>myomectomy</kwd><kwd>recurrent pregnancy loss</kwd><kwd>preterm birth</kwd><kwd>uterine rupture</kwd><kwd>pregnancy complications</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>миома матки</kwd><kwd>миомэктомия</kwd><kwd>невынашивание беременности</kwd><kwd>преждевременные роды</kwd><kwd>разрыв матки</kwd><kwd>осложнения беременности</kwd></kwd-group><kwd-group xml:lang="zh"><kwd>子宫肌瘤</kwd><kwd>子宫肌瘤切除术</kwd><kwd>流产</kwd><kwd>早产</kwd><kwd>子宫破裂</kwd><kwd>妊娠并发症</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Adamyan LV, Andreeva EN, Suhih GT, et al. 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