V.F.Snegirev Archives of Obstetrics and GynecologyV.F.Snegirev Archives of Obstetrics and GynecologyАрхив акушерства и гинекологии им. В.Ф. Снегирева2313-87262687-1386Eco-Vector11103010.17816/2313-8726-2022-9-3-153-161Original study articlesОригинальные исследованияOriginal study articlesResearch ArticleRisk factors for premature placental abruption: a retrospective observational comparative studyФакторы риска преждевременной отслойки плаценты: ретроспективное обсервационное сравнительное исследованиеhttps://orcid.org/0000-0003-2131-487XRudakovaIrina S.РудаковаИрина Сергеевна
Russian Federation

Postgraduate Student, Obstetrician-Gynecologist

аспирант, врач акушер-гинеколог

irinarudakova21@gmail.comhttps://orcid.org/0000-0002-6113-8498ShifmanEfim M.ШифманЕфим Муневич
Russian Federation

MD, Dr. Sci. (Med.), Рrofessor

д.м.н., профессор

eshifman@mail.ruhttps://orcid.org/0000-0003-1128-9666TikhovaGalina P.ТиховаГалина Петровна
Russian Federation

research associate

научный сотрудник

tikhovag@gmail.ruPetrozavodsk State UniversityПетрозаводский государственный университетRepublican Perinatal CenterРеспубликанский перинатальный центрMoscow Regional Research Clinical Institute named after M.F. VladimirskyМОНИКИ им. М.Ф. Владимирского23092022931531612309202223092022Copyright ©; 2022, Rudakova I.S., Shifman E.M., Tikhova G.P.Copyright ©; 2022, Рудакова И.С., Шифман Е.М., Тихова Г.П.2022Rudakova I.S., Shifman E.M., Tikhova G.P.Рудакова И.С., Шифман Е.М., Тихова Г.П.https://creativecommons.org/licenses/by-nc-nd/4.0/https://archivog.com/2313-8726/article/view/111030

AIM: This study aimed to determine the risk factors for premature placental abruption (PPA).

MATERIALS AND METHODS: A retrospective comparative study was conducted at the Republican Perinatal Center of Petrozavodsk. The study group included 106 patients with a confirmed diagnosis of PPA from 2007 to 2017. The control group (comparison) included 106 women without PPA and abnormal placenta.

RESULTS: The statistical data analysis revealed the following risk factors of PPA: lack of higher education in the patient (odds ratio [OR]: 0.51, 95% confidence interval [CI]: 0.28–0.90); smoking (OR: 3.41, 95% CI: 1.29–8.97); chronic liver disease (OR: 7.29, 95% CI: 1.60–33.06); uterine abnormalities (OR: 8.57, 95% CI: 1.05–69.79); and pelvic inflammatory disease (OR: 6.12, 95% CI: 2.56–14.62). The effect of chronic hypertension, chronic kidney disease, and anemia on the occurrence of PPA in our study was not significant.

CONCLUSION: An increased risk of PPA was found in patients who smoke without higher education with chronic liver disease, uterine abnormalities, and pelvic inflammatory diseases.

Цель работы ― изучить факторы риска возникновения преждевременной отслойки плаценты (ПОП).

Материалы и методы. Проведено ретроспективное сравнительное исследование в Республиканском перинатальном центре Петрозаводска. В группу исследования включили 106 пациенток с подтверждённым диагнозом ПОП за 2007–2017 гг. В группу контроля (сравнения) вошли 106 женщин без ПОП и аномальной плацентации.

Результаты. Статистический анализ данных нашего исследования выявил следующие факторы риска возникновения ПОП: отсутствие у пациентки высшего образования ― ОШ 0,51; 95% ДИ 0,28–0,90; курение ― ОШ 3,41; 95% ДИ 1,29–8,97; хронические заболевания печени ― ОШ 7,29; 95% ДИ 1,60–33,06; аномалии развития матки ― ОШ 8,57; 95% ДИ 1,05–69,79; воспалительные заболевания органов малого таза ― ОШ 6,12; 95% ДИ 2,56–14,62. Влияние хронической артериальной гипертензии, хронической болезни почек и анемии на возникновение ПОП в нашем исследовании не было достоверно значимым.

Заключение. Выявлен повышенный риск ПОП у курящих пациенток без высшего образования с хроническими заболеваниями печени, аномалиями развития матки и воспалительными заболеваниями органов малого таза.

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